| Feature | Class I | Class II | Class III |
|---|---|---|---|
| Personnel Protection | Yes | Yes | Yes (Maximum) |
| Product Protection | No | Yes | Yes (Maximum) |
| Environmental Protection | Yes | Yes | Yes (Maximum) |
| Airflow Direction | Inward | Downward laminar + inward | Inward (gas-tight) |
| HEPA Filters | Exhaust only | Supply and exhaust | Double exhaust or exhaust + incineration |
| Typical Use Level | BSL-1, BSL-2, BSL-3 (aerosol-generating procedures) | BSL-1 to BSL-3 | BSL-1 to BSL-4 (highly infectious agents) |
| Chemical Use | Small amounts with proper ventilation | Type A: not suitable for volatile chemicals unless ducted; Type B: suitable for varying amounts of chemicals | Yes (safe for use) |





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